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Conditions/Pneumonia
Bacterial, viral, fungal

Pneumonia.

U.S. prevalence
~1.5M U.S. cases/yr
Kills >40,000 Americans every year. Common reason for hospital admission in adults 65+.

Pneumonia is an infection of the lung tissue.

Bacteria, viruses, or fungi cause inflammation in the air sacs (alveoli), which fill with fluid or pus — making it harder for oxygen to cross from the lung into the bloodstream. The most common bacterial cause is Streptococcus pneumoniae; viral causes (influenza, RSV, COVID, etc.) are also frequent.

The graph to understand

CURB-65 score vs. 30-day mortality risk.

Score 0–1: less than 2% mortality — candidates for outpatient treatment. Score 2: approximately 9% mortality — admit and monitor. Score 3–5: 15–40% mortality — consider ICU. The risk gradient is steep and the scoring is fast (five yes/no questions).

00.7%12.1%29.2%314.5%440%557%CURB-65 score · 30-day mortality (Lim 2003)
Score 2 · Admit / monitor
9.2%
Confusion · Urea · Respiratory rate · Blood pressure · Age 65+
Reference
01What it is
02How it shows up", body: "Classic symptoms include fever, productive cough with colored sputum, shortness of breath, chest pain that worsens with deep breath, fatigue, and chills. Older patients often present atypically — confusion, weakness, or simply "not themselves" — without the textbook fever and cough.
03How we diagnose it
04How we treat it
05What you can do

What it is

Pneumonia is an infection of the lung tissue. Bacteria, viruses, or fungi cause inflammation in the air sacs (alveoli), which fill with fluid or pus — making it harder for oxygen to cross from the lung into the bloodstream. Pneumonia kills more than 40,000 Americans every year. It is one of the most common reasons for hospital admission, especially in adults over 65. Among community-acquired pneumonia, the most common bacterial cause is Streptococcus pneumoniae.

How it shows up", body: "Classic symptoms include fever, productive cough with colored sputum, shortness of breath, chest pain that worsens with deep breath, fatigue, and chills. Older patients often present atypically — confusion, weakness, or simply "not themselves" — without the textbook fever and cough.

How we diagnose it

Diagnosis combines symptoms, exam (crackles on lung auscultation), chest X-ray (showing infiltrate), and sometimes blood and sputum cultures. CT chest is helpful in unclear cases or when an underlying lung process is suspected. Viral testing identifies flu, RSV, COVID, and other viral causes.

How we treat it

Most healthy adults with mild community-acquired pneumonia can be treated as outpatients with oral antibiotics. Sicker patients need hospitalization for IV antibiotics, oxygen, and monitoring. Patients with severe pneumonia may need ICU care. The decision of inpatient vs. outpatient is informed by severity scores like CURB-65, which assess Confusion, Urea, Respiratory rate, Blood pressure, and age (65+). For viral pneumonia, antivirals (oseltamivir for influenza, paxlovid for COVID, ribavirin for select RSV) shorten illness and reduce complications when given early.

What you can do

  • Get vaccinated against pneumococcus, flu, COVID, and RSV.
  • Don't ignore prolonged cough with fever, especially after another viral illness — secondary bacterial pneumonia is common.
  • If you're over 65 or have a chronic lung condition, seek care early. Mortality climbs steeply with delayed treatment.
  • Complete your antibiotic course even if you feel better.
References
  1. 01
    Lim WS, van der Eerden MM, Laing R, et al. Defining community acquired pneumonia severity on presentation to hospital (CURB-65). Thorax. 2003;58(5):377–382.
    PMID: 12728155
  2. 02
    Metlay JP, Waterer GW, Long AC, et al. Diagnosis and Treatment of Adults with Community-acquired Pneumonia (ATS/IDSA). Am J Respir Crit Care Med. 2019;200(7):e45–e67.
    PMID: 31573350

This page is general medical information, not personalized medical advice. If you have questions about your specific health, talk with your Nimbus clinician.

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